Xindi Yin's PhD Defence
Alkaline phosphatases (AP), a group of glycoproteins attached on the apical mucosal membrane of the gut, are crucial for maintaining gut microbiome, health, and whole-body homeostasis. The endogenous AP digestive capacity is contributed by intestinal-type AP (IAP) isoforms and/or tissue-nonspecific AP (TNAP) isoforms in the porcine intestine. This research was conducted to elucidate the effects of in-feed therapeutic antibiotic Aureomycin on growth performances, gut permeability, intestinal AP functionality and genomic determinants of the AP isoforms in weanling pigs.