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Nicole Moran


Position/Title: M.Sc. (Thesis) Student
email: morann@uoguelph.ca
Phone: 4165785721
Office: N/A (please email for appointment)


 

During my BSc in Animal Biology, I worked on a research project under Dr. Niel Karrow that inspected the use of CpG DNA as a vaccine adjuvant in aquaculture species and agriculture species. I soon became interested in vaccine alternatives and the impacts of antimicrobial resistance. I completed my BSc Honours in Animal Biology at the University of Guelph in April 2018, and I am now continuing my education by pursuing my MSc under the supervision of Dr. Niel Karrow by determining the effects of phytochemicals on bacterial resistance in zebrafish.

Antimicrobial resistance occurs when microbes are able to resist the medications that were once effective in managing said microbes. In recent years, antimicrobial resistance has become a growing concern both in the agriculture industry and in the human health sciences. Examples of antimicrobial resistant bacteria include Salmonella Dublin, influenza virus, and Staphylococcus Aureus. My research focuses on alternative methods of treating the infections caused by these organisms such as phytochemicals and adjuvants that utilize the neuroendocrine immune system. Using zebrafish (Danio rerio) as a model organism, we will be giving our experimental animals one of two chosen chemicals, then challenging with classic MAMPs. This information will then be used to develop alternative methods to prophylactic vaccination in both aquaculture species and other agriculture species.

After the completion of this project, I hope to continue in academia and start my PhD studies focusing on immune pathways in zebrafish. When I am not working on my studies, I am either getting active in the gym, playing with my furry friends, or cooking up a storm!